What are the symptoms of AIDS?

0 votes
asked in Others by COURTNEY
What are the symptoms of AIDS?

4 Answers

0 votes
answered by LETICIA
The clinical staging of one, HIV infection
In clinical, it is divided into three stages, which are acute, asymptomatic and AIDS.
1. acute phase
This acute infection usually occurs about 2~4 weeks after initial exposure to HIV. During this period, a large number of HIV replication and CD4 cells decreased sharply, which is about 50 ~ 70% of those infected with flu like symptoms such as fever, sore throat, headache, rash, muscle and joint pain, swollen lymph nodes. Most of the symptoms were mild and lasts for 1-3 weeks. In addition, HIV can detect virus components in peripheral blood for about 5 days in the body, such as HIV-RNA and P24 antigen, and the antibody appears only a few weeks after the infection.
In addition, about 9% of the patients had acute HIV meningitis. The clinical manifestations included fever, headache, vomiting and meningeal irritation. Cerebrospinal fluid examination showed increased mononuclear cells and increased protein content.
2. asymptomatic period
This period can be extended by the symptoms of primary HIV infection or acute infection. There are no symptoms in the clinic, but the antibody of HIV and HIV core protein and envelope protein can be detected in the serum, and it is contagious. The length of this period is related to many factors, such as the number, type, route of infection, immune status and so on. The duration of each individual disease is different. Its duration is usually 6-8 years. It is generally believed that the period of infection by blood channels is shorter (from a number of months to 5 years, an average of 2 years), while the sexual pathway is longer (6~12 years, an average of 8 years).
In the asymptomatic period, HIV has maintained a highly balanced replication state in the human body, that is, a large number of viruses are produced every day, but at the same time, it is also largely cleared away, constantly infected and killed T lymphocytes, and constantly mutated to evade the pursuit of the immune system. The results showed as a whole in the HIV infected person:
The T cells decreased gradually, with the decline in the number of reports per year is 40 ~ 60/mm3;
The virus in the blood volume to maintain the low level constant, relative dynamic equilibrium, but this is not an absolute state of rest, but HIV continue to produce dynamic balance is continuously removed from the dynamic process; this fast paced high rate, has been confirmed in a lot of research in;
The rapid genetic mutation, from the study of the pathogenesis, this stage is a slow phase defect of CD4 cells, the slow immune function injury to patients with a potentially fatal risk of infection.
3. period of AIDS
The final stage after infection of HIV. The number of CD4+ T lymphocytes in the patients decreased significantly, more <200/mm3, and the viral load of HIV plasma increased significantly. The main clinical manifestations of this period are HIV related symptoms, various opportunistic infections and tumors.
In the asymptomatic period after a long time, the patient can have unexplained fever, fatigue, weight loss and progressive neurological symptoms such as headache, epilepsy, dementia, paralysis of the lower limbs, and then "opportunistic" infection, most showed Pneumocystis cysts of pulmonary inflammation or infection of the CNS. This is the most direct cause of mortality in patients with AIDS. The average survival time for untreated people after entering this period was 12~18 months.
This period can be sustained systemic lymphadenopathy (PGL), its characteristics are as follows: two. In addition to the groin outside of two or more parts of the lymph node enlargement; 2. Lymph node diameter is larger than 1cm, no tenderness, no adhesion; the duration of 3 months or more.
In addition, about 35% of the AIDS or HIV-1 infection will appear card Posey's sarcoma, it is a purple patch, can appear in the skin, but common in the limbs, also appeared in the oral mucosa, skin lesions of nearby lymph nodes may also be involved, local skin damage may develop ulcers or fungal infection is not easy healing, occasionally this plaque can also be seen in visceral and spread, but the card Posey's sarcoma HIV-1 infection does not constitute a cause of death, the direct cause of death is still the last infection patients. There are also a small number of HIV-1 infected people with lymphosarcoma, melanoma and other malignant tumors.
Three types of clinical types of two and HIV infection
(1) typical progresses
In the early stage of infection, its immune function was not damaged, but the immune ability gradually declined within 8~10 years, and finally became AIDS.
(2) fast progressed
The CD4 cell count of this group decreased rapidly within 2~5 years, the antibody level against HIV was very low, and the antibody neutralization ability of HIV was also poor, and there might be an enhanced antibody. The most significant feature of the fast progressed is that the high viral load has been maintained after HIV infection.
(3) long term survivors (also known as long-term non progressors)
These infected people can maintain a healthy state for more than 12 years, the longest has been up to 17 years, and the count of CD4 cells is normal. The proportion of the population in all infected people is 8 to 10%, most of which are hemophilia, intravenous drug users, heterosexual contacts and newborns. Long term survivors often have the following characteristics: low viral load (plasma and PBMC) and HIV were relatively non pathogenic strains and antibodies to individual HIV strains not existing aggravating infection, PBMC type cytokines and CD8 cell antiviral response is very strong.
The related factors of long-term survival include:
The infected with the attenuated strain replication ability (Nef deletion);
The strong CD8 cellular antiviral response;
The production of Th1 type cytokines (IL-2, IFN- y, IL-12);
The neutralizing antibody can be detected by its strain;
The human body is strong;
Such a CCR5 deletion allele, reduce the expression of CCR5 receptor on CD4 cells, affect the spread of NSI strain.
0 votes
answered by FANNIE
Initial symptoms of AIDS: the main manifestations are fever, night sweats and diarrhea for more than one month, and more than 10% of weight loss.
Some of the patients showed neuropsychiatric symptoms, such as memory impairment, mental indifference, personality change, headache, epilepsy and dementia.
The early symptoms of AIDS gastrointestinal symptoms: cough with hemoptysis, dyspnea, diarrhea, vomiting, abdominal pain, gastrointestinal bleeding, difficulty swallowing, loss of appetite, oral leukoplakia and oral ulcer, rash, decreased vision, blindness, seizures, paralysis, emaciation, anemia, two fecal incontinence, urinary retention, intestinal obstruction.
The initial symptoms of AIDS also have persistent systemic lymphadenopathy, which is characterized by:
(1) there were two or more than two parts of the lymph nodes except the groin.
The lymph node diameter is larger than 1cm, no tenderness, no adhesion;
(3) for more than 3 months.
Some people in the initial stage of AIDS symptoms will be like a cold, of course, some people have no symptoms completely, and they have no awareness of the infection of AIDS.
Some people have appeared the same symptoms as AIDS in the early stage is not necessarily AIDS, AIDS must be tested.
0 votes
answered by FRANCIS
Not every infected person will have a complete four stage performance, but each stage of the disease can be seen in the clinic. The different clinical manifestations of the four periods are a progressive and coherent course of development.
1. stage of acute infection
The window period is also at this time. The response of HIV to the body's stimulation after the invasion of the human body. Patients with fever, rash, lymph node enlargement, fatigue, sweating, nausea, vomiting, diarrhea, pharyngitis and so on. Some also appear acute aseptic meningitis, which is characterized by headache, neurogenic symptoms and meningeal irritation. At the end of the blood test, the total number of leukocytes was normal, or the lymphocyte decreased, and the mononuclear cells increased. At the time of acute infection, the symptoms are often mild and easy to be ignored. After infected 2--6 weeks, the serum HIV antibody showed positive reaction. Since then, there is a relatively healthy, asymptomatic incubation period.
(1) skin damage in the period of acute infection of AIDS
The mucous membrane of the skin is one of the main parts of the invasion of AIDS. Skin damage is mainly characterized by rash, mostly itchy red erythematous papules, and occasionally diffuse urticaria or water herpes. Skin lesions occur mostly in the face, trunk and heavy body. Many AIDS patients are the first symptom of skin damage.
(2) systemic symptoms in the period of AIDS acute infection
Systemic symptoms include: sore throat, fever, night sweats, joint pain, lymphadenopathy and hepatosplenomegaly. Chronic diarrhea is also a very obvious early clinical manifestation of some AIDS patients. The most common clinical symptoms of AIDS patients are recurrent low fever, chills, emaciation, fatigue, weight loss (5~22 kg), lethargy, weakness, inability to support normal physical activity, and no fever, diarrhea and weight loss.
(3) central nervous system symptoms during acute infection
About 9% of patients with nervous system injury may have acute HIV meningitis. The clinical manifestations are fever, headache, vomiting and meningeal irritation. Cerebrospinal fluid examination shows increased mononuclear cells and increased protein content. The above symptoms can be recovered by themselves after 2~3 weeks. The clinical manifestations of 20% to 40% of AIDS patients have neurologic diseases. The disorder of the nerve has been recognized as a common cause of disease and death in AIDS patients. The symptoms of the central nervous system coexist with the symptoms of various opportunistic infections, and are more common with subacute encephalitis.
(4) lymph node enlargement in acute infection period
The incidence of generalized lymphadenopathy, which is not explained by other reasons, is likely to be associated with HIV infection, with a incidence of 55% to 100%. The degree of lymph node enlargement is associated with the level of HIV antibody titer in the serum, often in the posterior cervical, submaxillary or subaxillary lymph nodes. The swollen lymph nodes are not fused, hard, even tenderness, and the surface of the skin is not changed.
2. incubation period
Latent period is also known as asymptomatic infection period. The infected person can not have any clinical symptoms, but the incubation period is not static, nor is it safe. The virus has a strong destructive effect in continuous reproduction. The incubation period refers to the time from infected HIV to the onset of clinical symptoms and signs of AIDS. The average incubation period of AIDS is now considered to be 2--10. This is very difficult for the early detection of patients and prevention. After the incubation period, 50% of the people will develop into AIDS within 8 years. It has been reported that from 1 to 7 years, the rate of infection from infection to disease is 1.5%, 5%, 10%, 15%, 25%, 30% and 40%. The incubation period of AIDS in children is short, with an average of 12 months. At this time, a very sensitive method was used to detect the number of virus nuclear wakes in the plasma of HIV infected people, and it could predict the incidence of the disease within 5 years.
3. prophase of AIDS
After the incubation period, signs and symptoms associated with AIDS, obviously, it was known as the AIDS related syndrome, also known as persistent generalized lymphadenopathy. The main manifestations are: persistent lymphatic enlargement, starting in the neck, and next to axillary and inguinal lymph nodes. In general, there are less than two cases of lymph node enlargement. The weight loss was over 10%. Periodic fever (about 38 degrees centigrade), often lasts for several months. Night sweats. There are various infections such as herpes simplex virus, Candida albicans (fungi) and so on.
4. typical AIDS period
As the immune system is seriously damaged, all kinds of fatal opportunistic infections, tumors and so on are very easy to occur. The lesions can be seen on the lungs, the mouth, the digestive system, the nervous system, the endocrine system, the heart, the kidneys, the eyes, the joints, the skin and so on. The average survival period was 9 months in the patients with opportunistic infection.
AIDS is not invincible, as long as the timely discovery of the early symptoms of AIDS, and establish the correct faith, some AIDS can be treated well, provided of course that we pay more attention to AIDS, grasp the early symptoms of AIDS, and apply to practice.
AIDS symptoms are not a problem, only by testing to determine whether you are infected. After the clinical statistics, many HIV infected people have no symptoms of AIDS awareness in the incubation period, but there are also some people early in the infection may have early symptoms of AIDS have a fever, sore throat, dizziness, weakness, joint pain, rash, superficial lymph nodes and other similar "cold", some people can the occurrence of diarrhea. The symptoms of AIDS usually disappear after 1-2 weeks, and then the patients turn to the latent period of no AIDS symptoms.
The common symptoms of aids include the following aspects:
0 votes
answered by KELLI
Initial symptoms of AIDS: the main manifestations are fever, night sweats and diarrhea for more than one month, and more than 10% of weight loss.
Some of the patients showed neuropsychiatric symptoms, such as memory impairment, mental indifference, personality change, headache, epilepsy and dementia.
The early symptoms of AIDS gastrointestinal symptoms: cough with hemoptysis, dyspnea, diarrhea, vomiting, abdominal pain, gastrointestinal bleeding, difficulty swallowing, loss of appetite, oral leukoplakia and oral ulcer, rash, decreased vision, blindness, seizures, paralysis, emaciation, anemia, two fecal incontinence, urinary retention, intestinal obstruction.
The initial symptoms of AIDS also have persistent systemic lymphadenopathy, which is characterized by:
(1) there were two or more than two parts of the lymph nodes except the groin.
The lymph node diameter is larger than 1cm, no tenderness, no adhesion;
(3) for more than 3 months.
Some people in the initial stage of AIDS symptoms will be like a cold, of course, some people have no symptoms completely, and they have no awareness of the infection of AIDS.
Welcome to OkoKHealth Questions and Answers, where you can ask questions related with health and receive answers from other members of the community.

Contact Us : admin@okokhealth.com
...