What are the causes of coronary heart disease?

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asked in Internal Medicine by LORETTA
What are the causes of coronary heart disease?

6 Answers

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answered by HANNAH
First, the cause of the disease
A large number of epidemiological studies on coronary atherosclerotic heart disease show that the following factors are closely related to the onset of coronary heart disease. These factors are called coronary heart disease predisposing factors (also known as risk factors).
1. age
This disease is often seen in people over 40 years of age. The occurrence of atherosclerosis may begin in children, and the incidence of coronary heart disease increases with age.
2. sex
Males are more common, and the ratio of male and female incidence is about 2: 1. Since estrogen has an anti atherosclerotic effect, the incidence of women in the postmenopausal period increases rapidly.
3. family history
There is a family history of coronary heart disease, diabetes, hypertension and hyperlipidemia, and the incidence of coronary heart disease is increased.
4. individual types
Type A personality (aggressive and competitive) have a higher prevalence of coronary heart disease, mental stress is easy to disease. It may be related to the high concentration of catecholamines in the body for a long time.
5. smoking
It is an important risk factor for coronary heart disease. The prevalence of coronary heart disease in smokers was 5 times higher than that of non smokers, and it was proportional to the amount of smoking. The carbon monoxide hemoglobin in the smoker's blood is increased, and the nicotine in the smoke reduces the blood vessels, causing the arterial wall to be anoxic and cause the arterial injury.
6. hypertension
It is an important risk factor for coronary heart disease. The patients with coronary heart disease in hypertension were 4 times as high as those of normal blood pressure, and 60% to 70% of the patients with coronary heart disease were suffering from hypertension. When the arterial pressure increases, the changes of shear stress and sidewall pressure can lead to intimal injury. At the same time, the increase of blood pressure leads to the infiltration of plasma lipids into the intimal cells, resulting in platelet aggregation and smooth muscle cell proliferation, and atherosclerosis.
7. hyperlipidemia
Hypercholesterolemia is an important risk factor for coronary heart disease. The risk of hypercholesterolemia (total cholesterol >6.76mmol/L, low density lipoprotein cholesterol >4.42mmol/L) is 5 times higher than that of normal subjects (total cholesterol <5.2mmol/L). Recent studies have shown that hypertriglyceridemia is an independent risk factor for coronary heart disease. High density lipoprotein has protective effect on coronary heart disease, and its lower value is susceptible to coronary heart disease. The ratio of high-density lipoprotein cholesterol to total cholesterol is <0.15, which is a valuable predictor of coronary atherosclerosis. Recent studies have found that serum α - lipoprotein [Lp (α)] concentration (>0.3g/L) is also an independent risk factor for coronary heart disease.
8. diabetes
It is an important risk factor for coronary heart disease. The risk of coronary heart disease in diabetic patients is 2 times higher than that in normal persons. The risk of coronary heart disease in female diabetic patients is 3 times higher than that in male patients, and it is easy to cause heart failure, death and death. Glycosylated low density lipoprotein in blood is increased when hyperglycemia is high, so that the degradation and metabolism of low density lipoprotein receptor pathway are inhibited. At the same time, hyperglycemia also damages the intima of blood vessels, and diabetes is often accompanied by abnormal lipid metabolism. Therefore, diabetic patients are prone to coronary heart disease.
9. obesity and too little exercise
(1) standard weight (kg) = height (CM) -105 (or 110). 2. Body mass index = weight (kg) / (height m) 2. Obesity was said to be more than a standard weight of 20% or a body mass index >24. Obesity is not as important as hypertension, hyperlipidemia, and diabetes, but obesity can indirectly affect coronary heart disease by promoting the development of these three factors. Exercise can adjust and improve endothelial function, promote patients to establish the coronary collateral circulation in patients with coronary heart disease, exercise less prone to obesity, so it should be fully aware of the urgency of the treatment of obesity and the importance of increasing the amount of exercise.
10. other
(1): a large number of long-term drinking alcohol damage function high spirits on the heart and blood vessels, liver and other organs, can lead to cirrhosis, alcoholic cardiomyopathy, hypertension and moderate drinking; low degree wine colored (e.g. Wine) can reduce the risk of coronary heart disease, because alcohol can increase high density lipoprotein concentration.
(2) oral contraceptives: long-term oral contraceptives can increase blood pressure, increase blood lipids and impaired glucose tolerance, while changing the clotting mechanism and increasing the chance of thrombosis.
(3) eating habits: eating high calorie, high animal fat, high cholesterol, high sugar diet is easy to suffer from coronary heart disease, and other changes in intake of trace elements.
Coronary atherosclerotic heart disease, and atherosclerosis is the component of blood cells, extracellular matrix, arterial wall (especially monocytes, platelets and LDL), the interaction of local hemodynamics, environmental and genetic factors results. Therefore, it should be noted that there is a risk factor for coronary heart disease, which is not equal to that of coronary heart disease.
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answered by MARYANN
Coronary heart disease (CHD) is also known as a coronary artery heart disease (coronary heart disease), which is a common heart disease. This disease is more serious, if the patient does not have a positive treatment, it will have a great impact on the life of the patient. So what is the disease of coronary heart disease? What is the cause of coronary heart disease?
What is the disease of coronary heart disease
1, the definition of coronary heart disease
From a clinical point of view, coronary heart disease is a heart disease caused by coronary artery obstruction or stenosis, and it is also known as ischemic heart disease. Coronary artery stenosis is caused by the accumulation of fat material through the inner wall of the vessel, which is also called arteriosclerosis. Once arteriosclerosis develops to a more serious degree, coronary artery stenosis will slowly aggravate and limit the amount of bleeding into the myocardium, resulting in angina pectoris.
2. Causes of coronary heart disease
There are many reasons for coronary heart disease in clinical practice, the most common is dyslipidemia, and blood lipid is the increase of total cholesterol and triglyceride and low density lipoprotein cholesterol in a flash. Secondly, according to data, the trend of coronary heart disease among obese friends is increasing. Once the body is overweight, it is easy to get coronary heart disease. In addition, frequent smoking can also cause a certain damage to the cardiovascular system, which makes the blood pressure rise and cause coronary heart disease.
These are the diseases of coronary heart disease and the cause of coronary heart disease. For patients with coronary heart disease, if we want to get good treatment, we must actively change their habits and habits, try to quit the research, take a low salt diet, and take part in some physical exercises properly, so as to achieve the purpose of controlling weight.
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answered by OLIVIA
Ten major causes of coronary heart disease
In order to treat coronary heart disease, first we have an analysis of what causes coronary heart disease and only find the reason to have better treatment. It is found that there are ten main causes of coronary heart disease.
1. Age related
The main population of coronary heart disease is middle-aged and elderly people over 40 years old, and it has progressed rapidly after 49 years of age. However, in recent years, the incidence of coronary heart disease has a trend of younger.
2. Sex related
Among American ethnic groups, the mortality rate of male coronary heart disease is significantly higher than that of women. In our country, the proportion of men and women is about 2: 1. However, after the menopause, the incidence of coronary heart disease has increased significantly due to the significant decrease of estrogen level. The related treatment shows that after 60, women are more than men.
3. It is related to the profession
Mental workers are generally larger than manual workers, because they are in a sense of oppression for a long time.
4. It is related to diet
Often eating high calorie diet, more animal fat and cholesterol are susceptible to this disease; therefore, to control the incidence of coronary heart disease, besides controlling the intake of high-fat diet, we must also pay attention to the control of food intake.
5. It is related to obesity
Obese people with super - standard weight are prone to coronary heart disease, especially those with rapid weight gain. However, it is believed that the study of weight evaluation should be paid more attention to. The body mass index should not be measured alone, but the thickness of subcutaneous fat should be measured. The prospective study data show that people with centripetal obesity have greater risk.
6. It is related to blood pressure
The increase of blood pressure is an independent risk factor for the onset of coronary heart disease. The risk of atherosclerosis caused by elevated blood pressure is 4 times as high as that of those in normal blood pressure.
7. It is related to smoking
Smoking is the main risk factor for coronary heart disease. Smokers compared with non smokers, the morbidity and mortality of the disease increased by 2~6 times, and was proportional to the number of daily smoking.
8, related to blood lipid
Because of genetic factors, excessive intake of fat, or disorder of lipid metabolism, dyslipidemia. Such as total cholesterol, triglyceride, LDL, VLDL increased, and HDL decreased, easy to suffer from this disease.
9. Related to diabetes
The fact that diabetes is easy to cause cardiovascular disease has been recognized. The data show that the incidence of this disease in diabetic patients is 2 times as high as that of non diabetic patients.
10. Related to heredity
In the family, there are 5 times more likely to be sick than the family without this condition.
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answered by JEANNETTE
A variety of diseases may lead to the occurrence of coronary heart disease
1 hyperlipidemia and hyperlipidemia are the risk factors of coronary heart disease, which are the earliest known risk factors. They are also the most dangerous risk factors for coronary artery in all risk factors. In the intervention treatment of coronary heart disease, cholesterol is the target of the first treatment. 2 high blood pressure and high blood pressure as a risk factor, compared with smoking is not inferior. China is a big country with high blood pressure. According to the statistics of the Ministry of health, about 110 million of the hypertensive patients in China have been treated, but only 30% have received medical treatment. 3 diabetic diabetes is also one of the risk factors for coronary heart disease, and diabetes almost impressions from the formation of atherosclerotic heart death in every link. In recent years, diabetes incidence in the population is growing rapidly and is abnormal and serious, most of patients with diabetes and diabetes do not know, did not receive effective treatment, but the complications after diagnosed as diabetes, at this time has been delayed time for treatment.
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answered by SHELLEY
Bad lifestyle is a high risk factor for coronary heart disease
1 smoking is one of the most important risk factors of coronary heart disease, at the same time if there are smoking and other risk factors, there are obvious synergistic effects, for example, the incidence of cardiovascular disease in patients with hypertension daily smoking a pack of cigarettes smoking cessation reduces 35%-40%. The study also confirmed that the risk of cardiovascular death was also significantly increased in passive smokers. Smoking can increase the risk of coronary artery spasm by 204 times. The risk of acute myocardial infarction or sudden coronary death is 2.7 times that of non-smokers, and 4.7 times that of women. 2 obesity and obesity is a risk factor for coronary heart disease, although there is still controversy, but there is no conclusion, but obesity is one of the risk factors of coronary heart disease. Obesity can lead to increased blood pressure, increased triglycerides and cholesterol levels, and protective high-density lipoprotein levels, and can cause hyperinsulinemia. It can be said that obesity is associated with all the risk factors for coronary heart disease except smoking. An ancient Chinese saying, "a thousand gold is difficult to buy old to be thin", indeed has a certain scientific truth.
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answered by WHITNEY
Supply of atherosclerotic plaque in the coronary artery wall of the heart itself causes cardiac lesions caused by stenosis of the vascular cavity. The clinical symptoms are different because of the difference in the number and degree of the coronary artery stenosis.
The etiology of this disease is not yet clear, but it is related to hypertension, hyperlipidemia, hyperviscosity, diabetes, hypofunction and age.
1, age and sex: the incidence of coronary heart disease increased after 40 years of age, and the incidence of pre menopausal women was lower than that of men, and it was equal to men after menopause.
2, hyperlipidemia: in addition to age, lipid metabolism disorder is the most important predictor of coronary heart disease. There is a close relationship between the levels of total cholesterol (TC) and low density lipoprotein cholesterol (LDLC) and the risk of coronary heart disease. The risk of coronary heart disease increased when the level of LDLC increased by 1%. 2-3%. glycerol three fat (TG) is an independent predictor of coronary heart disease, often accompanied by low HDLC and impaired glucose tolerance. The latter two are also risk factors of coronary heart disease.
3, hypertension: hypertension is closely related to the formation and development of coronary atherosclerosis. Systolic blood pressure can predict coronary heart disease events more frequently than diastolic blood pressure. Systolic blood pressure of.140-149mmhg is more than 90-94mmhg's diastolic blood pressure, which can increase the risk of coronary heart disease.
4, smoking: smoking is an important risk factor for coronary heart disease, and it is the only most avoidable cause of death. There is a significant dose - response relationship between coronary heart disease and smoking.
5, diabetes: coronary heart disease is the primary cause of death in the patients with minor diabetes. Coronary heart disease accounts for nearly 80% of all the causes of death and the rate of hospitalization.
6, obesity: has been defined as the primary risk factor for coronary heart disease, and can increase the mortality of coronary heart disease. Obesity was defined as body mass index (BMI= weight (kg) / height square (M2)) in male >=27.8, female >=27.3.BMI and TC, TG increased, and HDL-C decline was positively correlated.
7, sedentary lifestyle: the risk of coronary heart disease and death of people who do not love sports will double.
8, there are still heredity, drinking, environmental factors and so on.
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